Cervical Vertebral Lesions in Equine Stenotic Myelopathy
| Autor: | K. J. McQuerry, Neil M. Williams, Seid W. Waddell, Michael J. Voor, Jennifer G. Janes, S. M. Reed, K. S. Garrett, James N. MacLeod |
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| Rok vydání: | 2015 |
| Předmět: |
Male
Pathology medicine.medical_specialty Articular processes Spinal Cord Diseases Myelopathy Osteosclerosis Spinal Stenosis Spinal cord compression medicine Animals Cyst Horses General Veterinary business.industry Anatomy X-Ray Microtomography medicine.disease Magnetic Resonance Imaging medicine.anatomical_structure Spinal Cord Osteochondrosis Cervical Vertebrae Histopathology Female Horse Diseases business Cervical vertebrae |
| Zdroj: | Veterinary pathology. 52(5) |
| ISSN: | 1544-2217 |
| Popis: | Skeletal lesions in the articular processes of cervical vertebrae C2 to C7 were compared between Thoroughbred horses with cervical stenotic myelopathy (17 males, 2 females; age, 6–50 months) and controls (6 males, 3 females; age, 9–67 months). Lesions identified by magnetic resonance imaging occurred with an increased frequency and severity in diseased horses and were not limited to sites of spinal cord compression. Lesions involved both the articular cartilage and trabecular bone and were further characterized using micro–computed tomography and histopathology. The most common histologic lesions included osteochondrosis, osseous cyst–like structures, fibrous tissue replacement of trabecular bone, retained cartilage matrix spicules, and osteosclerosis. Osseous cyst–like structures were interpreted to be true bone cysts given they were a closed cavity with a cellular lining that separated the cyst from surrounding bone. This is the first report of bone cysts in the cervical articular processes of horses with cervical stenotic myelopathy. The morphology and distribution of the lesions provide additional support for the previously proposed pathogenesis that developmental abnormalities with likely secondary biomechanical influences on the cervical spine contribute to equine cervical stenotic myelopathy. |
| Databáze: | OpenAIRE |
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