Emergencia de resistencia a macrólidos en Streptococcus pyogenes
| Autor: | Marcela Cifuentes D, Valeria Prado J, Claudia Vinagre del P, Alicia Ojeda S, Francisca Valdivieso R |
|---|---|
| Jazyk: | Spanish; Castilian |
| Rok vydání: | 1999 |
| Předmět: |
medicine.drug_class
Cephalosporin Clindamycin Erythromycin General Medicine Bacterial Infections Biology Antibiotics Macrolide medicine.disease_cause Agar dilution Microbiology Penicillin Minimum inhibitory concentration Antibiotics Streptococcus pyogenes medicine Vancomycin Gram-Positive Bacterial Infections medicine.drug |
| Zdroj: | Revista médica de Chile, Volume: 127, Issue: 12, Pages: 1447-1452, Published: DEC 1999 Revista médica de Chile v.127 n.12 1999 SciELO Chile CONICYT Chile instacron:CONICYT |
| Popis: | Background: Diseases produced by Streptoccocus pyogenes are still a problem in Chile, as in the rest of the world. It exhibits in vitro susceptibility to different antimicrobials, but penicillin continues to be the treatment of choice. Alternative drugs have been developed for allergic patients, such as erythromycin, new macrolides and cephalosporins. Nevertheless, resistant strains are appearing due to the indiscriminate use of macrolides. Aim: To assess present antimicrobial susceptibility of S Pyogenes strains isolated from chilean patients. Material and Methods: The susceptibility to penicillin, macrolides, clindamycin, cephalotin and vancomycin of 153 S Pyogenes strains, obtained from different health centers of the Metropolitan Region and isolated between 1996 and 1998, was assessed using the Kirby-Bauer method. Agar dilution minimal inhibitory concentration was then determined to macrolide resistant strains. Results: All strains were susceptible to penicillin. There was a 7.2% cross-resistance to macrolides. Conclusions: These results confirm that S Pyogenes resistance to macrolides has increased considerably in the Metropolitan Region of Chile during the last years. |
| Databáze: | OpenAIRE |
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