Loss of smell in patients with traumatic brain injury is associated with neuropsychiatric behavioral alterations
| Autor: | Eduardo Lehrer, Montserrat Bernabeu, Joan Berenguer, Franklin Mariño-Sánchez, Isam Alobid, Concepció Marin, Sara Laxe, Cristobal Langdon, Llorenç Quintó, Joaquim Mullol |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
medicine.medical_specialty Traumatic brain injury Anosmia Neuroscience (miscellaneous) Audiology Rating scale Brain Injuries Traumatic Developmental and Educational Psychology medicine Humans Glasgow Coma Scale In patient Prospective Studies olfactory disorder Prospective cohort study business.industry Loss of smell traumatic brain injury Cognition Neuropsychiatric inventory medicine.disease Smell neuropsychiatric disorders head trauma Female Neurology (clinical) OLFACTORY IMPAIRMENT business |
| Zdroj: | Brain Injury r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol instname |
| ISSN: | 1362-301X 0269-9052 |
| DOI: | 10.1080/02699052.2021.1972447 |
| Popis: | Objective We sought to identify and correlate the severity of traumatic brain injuries (TBIs) associated with olfactory dysfunction with cognitive and behavioral profiles. Participants and setting Patients with TBI undergoing treatment in a specialized neuro-rehabilitation hospital. Design Prospective study. Main measures Glasgow Coma Scale (GCS) at the time of injury and during posttraumatic amnesia. Motor functions were assessed with the Functional Instrument Measure and Disability Rating Scales. The Wechsler Adult Intelligence test was used for neuropsychologic assessment and the Neuropsychiatric Inventory was used to assess behavioral changes. The Barcelona Smell Test-24 was used to study subjective smell loss. Results A total of 111 patients with TBI were enrolled (33 females; mean age 32.86 years); 38.73% exhibited smell loss. Patients with no olfactory impairment (OI) had worse TBIs than those with OI (GCS scores 5.65 and 7.74, respectively); no significant differences in cognitive behaviors, such as attention memory, visuoperception, and visuoconstruction, were observed. However, patients with TBI and olfactory dysfunction showed statistically significant alterations in neuropsychiatric behavioral performances such as feeding when compared with patients with TBI without smell loss. Conclusion Olfactory dysfunction in patients with a TBI correlates with altered neuropsychiatric behavioral performances such as feeding, sleeping, and motor behavior. |
| Databáze: | OpenAIRE |
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