Testing for haplotype sharing by siblings with incomplete information of parental haplotypes

Autor:	D. M. Grennan, J. R. Green
Rok vydání:	1991
Předmět:	Genetics Male Parents Haplotype Inheritance (genetic algorithm) Genetic Diseases Inborn Disease susceptibility gene Biology Nuclear Family Genetic Techniques Haplotypes Complete information Humans Female Haplotype sharing Genetics (clinical)
Zdroj:	Annals of human genetics. 55(3)
ISSN:	0003-4800
Popis:	SUMMARY Testing for the inheritance of a disease susceptibility gene by analysis of haplotype sharing among affected siblings has been well established for the case where all four parental haplotypes have been ascertained. This paper presents a modification of a published method to cover the situation where there is incomplete information concerning parental haplotypes and this new test is applied in a worked example.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f8585625e86eb2a382e75ccdaad946a https://pubmed.ncbi.nlm.nih.gov/1763887 Zobrazit plný text záznamu Plný text