Simkania negevensis, an Example of the Diversity of the Antimicrobial Susceptibility Pattern among Chlamydiales
| Autor: | Gilbert Greub, David Baud, Manon Vouga |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Animals Anti-Bacterial Agents/pharmacology Cell Line Cercopithecus aethiops Chlamydiaceae Infections Chlamydiales/drug effects Clindamycin/pharmacology Macrolides/pharmacology Microbial Sensitivity Tests Quinolones/pharmacology Rifampin/pharmacology Vancomycin/pharmacology Vero Cells beta-Lactams/pharmacology Chlamydiales Simkaniaceae intracellular bacteria Antimicrobial susceptibility Quinolones beta-Lactams Microbiology 03 medical and health sciences Vancomycin Chlorocebus aethiops medicine Pharmacology (medical) Pharmacology biology Intracellular parasite Clindamycin biology.organism_classification Anti-Bacterial Agents 030104 developmental biology Infectious Diseases Susceptibility Simkania negevensis Macrolides Rifampin Bacteria medicine.drug |
| Zdroj: | Antimicrobial Agents and Chemotherapy Antimicrobial agents and chemotherapy, vol. 61, no. 8, pp. 1-5 |
| ISSN: | 1098-6596 0066-4804 |
| Popis: | In past years, several Chlamydia -related bacteria have been discovered, including Simkania negevensis , the founding member of the Simkaniaceae family. We evaluated the antimicrobial susceptibility patterns of this emerging intracellular bacterium and highlighted significant differences, compared with related Chlamydiales members. S. negevensis was susceptible to macrolides, clindamycin, cyclines, rifampin, and quinolones. Importantly, unlike other Chlamydiales members, treatment with β-lactams and vancomycin did not induce the formation of aberrant bodies, leading to a completely resistant phenotype. |
| Databáze: | OpenAIRE |
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