Vaginal delivery in a patient with pheochromocytoma, medullary thyroid cancer, and primary hyperparathyroidism (multiple endocrine neoplasia type 2A, Sipple′s syndrome)
| Autor: | Muhammad Anas Muzannara, Vassilios Dimitriou, Mahmood Nasir, Georges Geldhof, Mohammed K Al Harbi, Nasser Tawfeeq |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Parathyroidectomy
Gynecology medicine.medical_specialty Hyperparathyroidism endocrine system endocrine system diseases Medullary thyroid cancer business.industry medicine.medical_treatment Thyroidectomy Case Report pheocromocytoma medicine.disease Pheochromocytoma Thyroid carcinoma lcsh:RD78.3-87.3 Anesthesiology and Pain Medicine multiple endocrine neoplasia 2A lcsh:Anesthesiology Medicine pregnancy business Multiple endocrine neoplasia Primary hyperparathyroidism |
| Zdroj: | Saudi Journal of Anaesthesia, Vol 8, Iss 3, Pp 437-439 (2014) Saudi Journal of Anaesthesia |
| Popis: | Multiple endocrine neoplasia 2A (MEN 2A), or Sipple's syndrome is a rare inherited dominant syndrome, characterised by medullary thyroid carcinoma, adrenal pheochromocytoma and hyperparathyroidism, due to specific RET proto-oncogene mutations. The women with MEN 2A syndrome are at risk of complicated pregnancy because of unrecognised pheochromocytoma and transmission of RET mutation to the progeny. We report a case of a woman with MEN 2A diagnosed in early pregnancy. Alpha-blockade medical therapy was used effectively and time was given for fetal maturation. Uncomplicated vaginal delivery performed under epidural analgesia. Six weeks postpartum adrenalectomy, thyroidectomy and parathyroidectomy were performed uneventfully. |
| Databáze: | OpenAIRE |
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