Acquired Pure Red Cell Aplasia and Recombinant Erythropoietin

Autor: Sandip K Panda, Somanath Padhi
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Indian Journal of Nephrology
Indian Journal of Nephrology, Vol 31, Iss 4, Pp 331-335 (2021)
ISSN: 1998-3662
0971-4065
Popis: Recombinant erythropoietin (rEPO)-associated immunologically driven acquired pure red cell aplasia (PRCA) is an underreported, potentially worsening clinical syndrome in the setting of treatment of anemia of chronic kidney disease. Most cases reported in world literature are related to different formulations of erythropoiesis-stimulating agents with an implication in diagnosis and management. This brief review highlights the clinical guidelines of rEPO usage in nephrology practice, the pathophysiologic mechanism of PRCA, clinical features, diagnosis, and suggested management protocols.
Databáze: OpenAIRE