Meeting report of the first European biotransformation workshop

Autor:	Lars Weidolf, Axel Pähler, Markus Walles, E M Isin
Rok vydání:	2021
Předmět:	Pharmacology chemistry.chemical_compound Biotransformation chemistry Health Toxicology and Mutagenesis Environmental chemistry Inactivation Metabolic Environmental science General Medicine Toxicology Xenobiotic Biochemistry
Zdroj:	Xenobiotica. 51:1081-1086
ISSN:	1366-5928 0049-8254
DOI:	10.1080/00498254.2021.1958027
Popis:	1. Challenges and opportunities in the field of biotransformation were presented and discussed at the 1st European Biotransformation workshop which was conducted virtually in collaboration with the DMDG 27 January 2021. Here we summarize the presentations and discussions from this workshop.The following topics were covered:2. Needs for radiolabel for IND filing versus quantitation without standards.3. Applications of cyclic ion mobility in the field of biotransformation.4. Computational predictions of xenobiotic metabolism.5. Future (outsourcing) needs in biotransformation.6. Genotoxicity risk assessment of metabolites and qualification of impurities using metabolite data.7. Regulatory aspects of MIST.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f760eb8345e3e619031a31662c9e0f8 https://doi.org/10.1080/00498254.2021.1958027 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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