Translational Research in Psoriasis
| Autor: | Joerg C. Prinz |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
business.industry Public health Translational research General Medicine Computational biology Pharmacology medicine.disease Prognosis Translational Research Biomedical Phenotype Rheumatology Basic research Predictive Value of Tests Risk Factors Psoriasis Genetic predisposition Medicine Animals Humans Genetic Predisposition to Disease business |
| Zdroj: | The Journal of rheumatology. Supplement. 93 |
| ISSN: | 0380-0903 |
| Popis: | Translational research is a coordinated process that converts scientific knowledge about diseases from basic research into the development of therapeutic or diagnostic procedures in order to improve public health. Recent insights into the pathogenesis of psoriasis have greatly promoted the rational development of new therapeutic approaches. The integration of genetic predisposition and pathogenetic events defined the cytokine cascade as a target for therapeutic interventions. Applying various phases of translational research has enabled development of novel therapies that combine high efficacy with convincing safety profiles, with important implications for public health. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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