Impact of the COVID-19 pandemic on the surveillance of antimicrobial resistance

Autor: Toshiki Kajihara, Aki Hirabayashi, Koji Yahara, Motoyuki Sugai, Keigo Shibayama
Rok vydání: 2021
Předmět:
Microbiology (medical)
PRSP
penicillin-resistant Streptococcus pneumoniae
Methicillin-Resistant Staphylococcus aureus
medicine.medical_specialty
Staphylococcus aureus
Coronavirus disease 2019 (COVID-19)
3GCR-EC
third-generation cephalosporin-resistant Escherichia coli
Klebsiella pneumoniae
S. pneumoniae
Streptococcus pneumoniae
Disease
K. pneumoniae
Klebsiella pneumoniae
Microbial Sensitivity Tests
medicine.disease_cause
AMRB
antimicrobial-resistant bacteria
Article
AMR
antimicrobial resistance
Antibiotic resistance
MSSA
methicillin-susceptible Staphylococcus aureus
Anti-Infective Agents
Internal medicine
Streptococcus pneumoniae
Pandemic
Drug Resistance
Bacterial
medicine
WHO-GLASS
World Health Organization-Global Antimicrobial Resistance Surveillance System
Humans
antimicrobial resistance
Pandemics
COVID-19
coronavirus disease
S. aureus
Staphylococcus aureus
CRP
carbapenem-resistant Pseudomonas aeruginosa
biology
3GCR-KP
third-generation cephalosporin-resistant Klebsiella pneumoniae
Pseudomonas aeruginosa
business.industry
SARS-CoV-2
MRSA
methicillin-resistant Staphylococcus aureus
E. coli
Escherichia coli
WHO-GLASS
COVID-19
General Medicine
biology.organism_classification
Anti-Bacterial Agents
Infectious Diseases
surveillance
business
JANIS
Japan Nosocomial Infections Surveillance
P. aeruginosa
Pseudomonas aeruginosa
Zdroj: The Journal of Hospital Infection
ISSN: 1532-2939
Popis: Summary Background The impact of the coronavirus disease (COVID-19) pandemic on antimicrobial resistance (AMR) is a major concern. Aim To compare the number of patients and isolation rate of antimicrobial-resistant bacteria before and after the beginning of the COVID-19 pandemic using the comprehensive national surveillance data. Methods We utilized comprehensive surveillance data, collected in the Japan Nosocomial Infections Surveillance programme, which included a total of 16.7 million samples of 5.9 million tested patients from >1300 hospitals. We compared the number of patients and isolation rate of five bacteria between 2019 and 2020, including antimicrobial-susceptible and -resistant bacteria of Staphylococcus aureus, Streptococcus pneumoniae, Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa. Findings The number of patients and isolation rate of S. aureus and meticillin-resistant S. aureus decreased slightly; those of S. pneumoniae and penicillin-resistant S. pneumoniae decreased by 60%; and those of third-generation cephalosporin-resistant K. pneumoniae increased. The isolation rate of the remaining bacteria apparently increased, although the number of patients decreased. This was due to a substantial decrease in the total number of tested patients (the denominator of the isolation rate), which was larger than that of the number of patients (the numerator of the isolation rate). Consistent results were obtained when the same data were re-aggregated using the procedure of the World Health Organization Global Antimicrobial Resistance Surveillance System, demonstrating the general importance of this problem. Conclusion Surveillance data during the COVID-19 pandemic must be carefully interpreted based on examination of the numerator, denominator and background factors that affect the denominator.
Databáze: OpenAIRE
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