Rocuronium for control of muscle spasms in a tetanus patient with chronic methamphetamine use disorder

Autor: Carissa Paz Dioquino Maligaso, Philip Asuncion Ramiro, Clare Angeli G. Enriquez, Joshua Emmanuel Edillon Abejero
Rok vydání: 2018
Předmět:
Zdroj: BMJ Case Reports. :bcr-2018
ISSN: 1757-790X
DOI: 10.1136/bcr-2018-224391
Popis: This is a case of a 31-year-old Filipino man with chronic methamphetamine use disorder who developed tetanus from a necrotic skin graft over his left calcaneus, which was fractured after a motor vehicular accident. During the course of his illness, the patient’s muscle spasms were unusually refractory to benzodiazepine, which is the first-line drug used in the management of muscle spasms. The muscle spasms were successfully controlled on the seventh day of illness with rocuronium at a dose of 10 μg/kg/min and midazolam at 0.30 mg/kg/hour. Both infusions were tapered off until the 23rd day of illness. The patient was discharged on the 30th day of illness, improved and stable.
Databáze: OpenAIRE