Views of Medical Doctors Regarding the 2013 WHO Adult HIV Treatment Guidelines Indicate Variable Applicability for Routine Patient Monitoring, for Their Family Members and for Themselves, in South-Africa

Autor: Matthew Chersich, Charles Feldman, Lee Fairlie, Willem D F Venter, Peter Cleaton-Jones
Jazyk: angličtina
Rok vydání: 2016
Předmět:
RNA viruses
0301 basic medicine
Sexual partner
Pediatrics
Medical Doctors
Health Care Providers
Breastfeeding
lcsh:Medicine
HIV Infections
Pathology and Laboratory Medicine
South Africa
chemistry.chemical_compound
Pre-exposure prophylaxis
0302 clinical medicine
Immunodeficiency Viruses
Antiretroviral Therapy
Highly Active

Surveys and Questionnaires
Medicine and Health Sciences
Public and Occupational Health
030212 general & internal medicine
lcsh:Science
Lipoatrophy
Multidisciplinary
Antimicrobials
Pharmaceutics
Drugs
Antiretrovirals
Viral Load
Middle Aged
Antivirals
Vaccination and Immunization
Professions
Medical Microbiology
Viral Pathogens
Viruses
Practice Guidelines as Topic
Pathogens
Viral load
Research Article
Adult
medicine.medical_specialty
Efavirenz
Anti-HIV Agents
Attitude of Health Personnel
Immunology
Antiretroviral Therapy
World Health Organization
Microbiology
03 medical and health sciences
Pharmacotherapy
Antiviral Therapy
Drug Therapy
Virology
Microbial Control
Physicians
Retroviruses
medicine
Adults
Humans
Family
Microbial Pathogens
Monitoring
Physiologic

Pharmacology
Treatment Guidelines
Health Care Policy
business.industry
Lentivirus
lcsh:R
Organisms
Biology and Life Sciences
HIV
Odds ratio
medicine.disease
030112 virology
Health Care
chemistry
Age Groups
Family medicine
People and Places
Population Groupings
Pre-Exposure Prophylaxis
lcsh:Q
Preventive Medicine
business
Viral Transmission and Infection
Zdroj: PLoS ONE, Vol 11, Iss 1, p e0145911 (2016)
PLoS ONE
ISSN: 1932-6203
Popis: South African doctors (n = 211) experienced in antiretroviral therapy use were asked via an online questionnaire about the WHO 2013 adult antiretroviral integrated guidelines, as well as clinical and personal issues, in three hypothetical scenarios: directing the Minister of Health, advising a family member requiring therapy amidst unstable antiretroviral supplies, and where doctors themselves were HIV-positive. Doctors (54%) favoured the 500 cells/μl WHO initiation threshold if advising the Minister; a third recommended retaining the 350 cells/μl threshold used at the time of the survey. However, they favoured a higher initiation threshold for their family member. Doctors were 4.9 fold more likely to initiate modern treatment, irrespective of their CD4 cell count, for themselves than for public-sector patients (95%CI odds ratio = 3.33–7.33; P
Databáze: OpenAIRE