Exploration of associations between deliberate self-poisoning and psychiatric disorders in rural Sri Lanka: A case-control study

Autor: S. U. B. Thennakoon, A. M. P. Adikari, Ranil Abeysinghe, Andrew H. Dawson, P. H. G. J. Pushpakumara, Thilini Rajapakse
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Male
Epidemiology
Alcohol use disorder
Geographical locations
Self Harm
Medicine and Health Sciences
Medicine
Big Five personality traits
Child
Depression (differential diagnoses)
Multidisciplinary
Alcohol Consumption
Depression
Organic Compounds
Mental Disorders
Absolute risk reduction
Middle Aged
Suicide
Chemistry
Physical Sciences
Female
Research Article
Adult
medicine.medical_specialty
Asia
Adolescent
Science
Personality Disorders
Young Adult
stomatognathic system
Mental Health and Psychiatry
Humans
Psychiatry
Aged
Sri Lanka
Nutrition
business.industry
Mood Disorders
Organic Chemistry
Case-control study
Chemical Compounds
Biology and Life Sciences
medicine.disease
Personality disorders
Diet
Case-Control Studies
Medical Risk Factors
Alcohols
Self poisoning
Sri lanka
People and places
business
Zdroj: PLoS ONE, Vol 16, Iss 8, p e0255805 (2021)
PLoS ONE
ISSN: 1932-6203
Popis: Psychiatric disorders are important predictors of deliberate self-harm. The present study was carried out to determine the associations between DSM-IV TR Axis- I & II disorders and deliberate self-poisoning (DSP) in a rural agricultural district in Sri Lanka. Patients residing in the district who presented with DSP were randomly selected for the study. Both the cases and age, sex, and, residential area, matched controls were assessed for DSM-IV TR Axis- I & II disorders based on the Structured Clinical Interview for DSM-IV-TR Axis I and II Disorders (SCID I & II) conducted by a specialist psychiatrist. Cases consisted of 208 (47.4%) males and 231 (52.6%) females. More than one third (37%) of males and more than half (53.7%) of females were aged below 20 years. DSM-IV TR axis-I and/or II psychiatric diagnoses were diagnosed in 89 (20.3%) of cases and 14 (3.2%) controls. Cases with a DSM-IV TR axis-I diagnosis were older than the cases without psychiatric diagnosis (32 and 19 years), p = 30 years and having an alcohol use disorder carried a 21 times excess risk for DSP. A fivefold excess risk for DSP was found among 10–19 year old females with borderline personality traits. Depressive disorder and alcohol-related disorders were significantly associated with the older participants who presented with DSP. The overall prevalence of psychiatric disorders associated with DSP in rural Sri Lanka was significantly lower compared to the rates reported in the West and other countries in the region. Therefore, health and research priorities to reduce self-harm in Sri Lanka should focus both on psychiatric and non-psychiatric factors associated with DSP.
Databáze: OpenAIRE