Changes in oral corticosteroid use in asthma treatment—A 20-year Danish nationwide drug utilisation study

Autor: Daniel Pilsgaard Henriksen, Hanne Madsen, Anton Pottegård, Inge Raadal Skov, Jesper Rømhild Davidsen
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Skov, I R, Henriksen, D P, Madsen, H, Pottegård, A & Davidsen, J R 2022, ' Changes in oral corticosteroid use in asthma treatment—A 20-year Danish nationwide drug utilisation study ', Basic & Clinical Pharmacology & Toxicology, vol. 130, no. 1, pp. 122-131 . https://doi.org/10.1111/bcpt.13680
Popis: Oral corticosteroids (OCS) are used in asthma management but can cause serious adverse effects. We aimed to investigate the usage trends in a nationwide asthma cohort in Denmark from 1999 to 2018. Using national registers, we identified young adults (18–45 years) with two or more asthma drug collections within 12 months since the age of 15 years as indicative of active asthma. OCS exposure level was stratified as high use (≥5 mg prednisolone/day/year) and low use (
Databáze: OpenAIRE