A concise synthesis of two pyrroles of marine origin

Autor:	Krzysztof Sienkiewicz, Charles W. Jefford, S. R. Thornton
Rok vydání:	1994
Předmět:	chemistry.chemical_classification Ketone Organic Chemistry Regioselectivity Intramolecular acylation Biochemistry chemistry.chemical_compound Ethanolamine Boron trihromide chemistry Acetylation ddc:540 Drug Discovery Organic chemistry Lewis acids and bases
Zdroj:	Tetrahedron Letters, Vol. 35, No 34 (1994) pp. 6271-6274
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(00)73409-5
Popis:	2-Ethanolamine and (2R)-2-aminopropanol were converted into their N-pyrrole derivatives, 14 and 15 , by reaction with 2,5-dimethoxytetrahydrofuran. The acetoxyacetyl derivatives of 14 and 15 were prepared and submitted to BBr 3 -promoted rearrangement. Acetylation of the resulting (2-acetoxyacetyl)pyrrol-1-yl-2-ethanol and 2-propanol furnished the corresponding acetates.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f55b1784c09b943aba0062e3c448e86 https://doi.org/10.1016/s0040-4039(00)73409-5 Zobrazit plný text záznamu