Treatment outcomes of transoral robotic and non-robotic surgeries to treat oropharyngeal, hypopharyngeal, and supraglottic squamous cell carcinoma: A multi-center retrospective observational study in Japan
| Autor: | Akira Shimizu, Daisuke Nishikawa, Ryuji Yasumatsu, Fumihiko Matsumoto, Shunsuke Miyamoto, Nobuhiko Oridate, Takashi Maruo, Yasushi Fujimoto, Tomonori Terada, Ken-ichi Nibu, Yo Kishimoto, Seiichi Yoshimoto, Kazunori Fujiwara, Tsutomu Ueda, Kiyoaki Tsukahara, Ichiro Tateya, Daisuke Sano, Terushige Mori |
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| Rok vydání: | 2021 |
| Předmět: |
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Natural Orifice Endoscopic Surgery medicine.medical_specialty Microsurgery medicine.medical_treatment Cohort Studies 03 medical and health sciences 0302 clinical medicine Japan Robotic Surgical Procedures Transoral robotic surgery medicine Humans Transoral laser microsurgery Registries 030223 otorhinolaryngology Aged Retrospective Studies Laryngoscopy business.industry Squamous Cell Carcinoma of Head and Neck Head and neck cancer technology industry and agriculture Margins of Excision Retrospective cohort study General Medicine medicine.disease Surgery body regions Radiation therapy stomatognathic diseases Otorhinolaryngology Head and Neck Neoplasms 030220 oncology & carcinogenesis Supraglottic Squamous Cell Carcinoma Cohort Female Laser Therapy business Chemoradiotherapy |
| Zdroj: | Auris, nasus, larynx. 48(3) |
| ISSN: | 1879-1476 |
| Popis: | The aim of this multicenter retrospective cohort study was to compare efficacy and subsequent postoperative treatment between transoral robotic surgery (TORS) and any non-robotic transoral surgery in Japanese patients with early oropharyngeal squamous cell carcinoma (OPSCC), hypopharyngeal SCC (HPSCC), or supraglottic SCC (SGSCC). Clinical information and surgical outcomes were compared between patients with early-stage OPSCC, HPSCC, and SGSCC who underwent TORS (TORS cohort) and those who underwent non-robotic transoral surgery, including transoral videolaryngoscopic surgery (TOVS), endoscopic laryngopharyngeal surgery (ELPS), and transoral laser microsurgery (TLM) (non-robotic cohort). The data of the Head and Neck Cancer Registry of Japan (registry cohort) were used to validate the comparison. The main outcomes were the presence of positive margins under pathology and the requirement for postoperative therapy, including radiotherapy or chemoradiotherapy. Sixty-eight patients in the TORS cohort, 236 patients in the non-robotic cohort, and 1,228 patients in the registry cohort were eligible for this study. Patients in the TORS cohort were more likely to have oropharyngeal tumor disease and T2/3 disease than those in the other cohorts (P Our results suggest that TORS leads to fewer positive surgical margins than non-robotic transoral surgeries. The clinical significance of TORS may be further validated through the results of all-case surveillance for patients who underwent TORS running in Japan in the future. |
| Databáze: | OpenAIRE |
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