Cephazolin and metronidazole prophylaxis in head and neck surgery
| Autor: | Phillip W. Saccogna, Melvin Strauss, Allan L. Allphin |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Male
medicine.medical_specialty Fistula medicine.medical_treatment Cefazolin Antitrichomonal Agents Esophageal Fistula Tracheotomy Risk Factors Metronidazole medicine Humans Surgical Wound Infection Antibacterial agent Retrospective Studies business.industry Neck dissection General Medicine Antibiotic Prophylaxis Middle Aged medicine.disease Surgery Cephalosporins Black or African American Regimen Logistic Models Otorhinolaryngology Head and Neck Neoplasms Anesthesia Drug Therapy Combination Female business Complication medicine.drug |
| Zdroj: | The Journal of laryngology and otology. 111(7) |
| ISSN: | 0022-2151 |
| Popis: | A seven-day course of cephazolin and metronidazole chemoprophylaxis for clean-contaminated head and neck oncological procedures is compared to results with previously published antibiotic regimens. Aetiological factors associated with increased rates of wound complications are analyzed. Retrospective analysis of procedures over asix-year period was performed. The overall wound complication rate was 28.1 per cent, comparing favourably with previously published results. A major fistula was the most common complication with a rate of 9.2 per cent. Factors statistically associated with increased rates of wound complications included: radical neck dissection, extended surgical procedures requiring flap reconstruction, previous tracheotomy, and race. This is the largest single institutional study to show thata seven-day course of cephazolin and metronidazole is an effective chemoprophylactic regimen in head and neck surgery. |
| Databáze: | OpenAIRE |
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