Comparison of point-of-care and laboratory glucose analysis in critically ill patients
| Autor: | Joánne Kuszaj, Caroline Domagtoy, Teresita Lacara, MaryClare Prasnikar, Lydia Snipes, Donna Lickliter, Kathy Quattrocchi |
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| Rok vydání: | 2007 |
| Předmět: |
Blood Glucose
Mean arterial pressure Education Continuing Fingerstick medicine.medical_treatment Critical Illness Point-of-Care Systems Blood Pressure Hematocrit Critical Care Nursing Southwestern United States Medicine Humans Diagnostic Techniques and Procedures Point of care medicine.diagnostic_test Critically ill business.industry General Medicine Carbon Dioxide Catheter Blood pressure Anesthesia business Central venous catheter |
| Zdroj: | American journal of critical care : an official publication, American Association of Critical-Care Nurses. 16(4) |
| ISSN: | 1062-3264 |
| Popis: | Background Blood for point-of-care analysis of glucose levels is often obtained from different sources (fingerstick, arterial or central venous catheter). Objectives To examine agreement between point-of-care and laboratory glucose values and to determine effects of hematocrit, serum carbon dioxide, and mean arterial pressure on the accuracy of point-of-care values. Methods Point-of-care values were compared with laboratory values. In 49 critically ill patients, blood was obtained first from a catheter for laboratory testing and then from the catheter and via fingerstick for point-of-care testing. Bias, precision, and root-mean-square differences were calculated to quantify differences in values between the 2 methods. A t test was used to determine differences in values between each point-of-care blood source and the laboratory value. Multiple regression analysis was used to determine if serum level of carbon dioxide, hematocrit, and/or mean arterial pressure significantly contributed to the difference in bias and precision for the point-of-care blood sources. Results Mean laboratory glucose level was 135 (SEM 5.3, range 58–265) mg/dL. In point-of-care testing, bias ± precision and root-mean-square differences were 2.1 ± 12.3 and 12.35, respectively, for fingerstick blood and 0.6 ± 10.6 and 10.46 for catheter blood. Values for point-of-care and laboratory tests did not differ significantly. For catheter samples, hematocrit and serum carbon dioxide contributed significantly to difference scores between point-of-care and laboratory values (P < .001). Conclusions Glucose values for point-of-care samples did not differ significantly from laboratory values. For catheter samples, hematocrit and serum carbon dioxide levels accounted for the difference between point-of-care and laboratory glucose values. |
| Databáze: | OpenAIRE |
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