Diagnosis, pathophysiology, and treatment of normal pressure hydrocephalus: A review of current perspectives
| Autor: | Anjali Mishra, Charchit Gupta, Pushpendra Nath Renjen, Dinesh Chaudhari |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
normal pressure hydrocephalus medicine.diagnostic_test Gait apraxia business.industry cerebral blood flow Urinary incontinence Magnetic resonance imaging medicine.disease Obstructive sleep apnea Cerebral blood flow Normal pressure hydrocephalus reversible dementia incontinence Genetics medicine Dementia Medicine Animal Science and Zoology medicine.symptom Intensive care medicine business Ventriculomegaly |
| Zdroj: | Apollo Medicine, Vol 17, Iss 1, Pp 10-15 (2020) |
| ISSN: | 2213-3682 0976-0016 |
| Popis: | Normal pressure hydrocephalus (NPH) is a potentially reversible syndrome characterized by enlarged cerebral ventricles (ventriculomegaly), cognitive impairment, gait apraxia, and urinary incontinence. A critical review of the current prospectives in the diagnosis and treatment of both idiopathic and secondary NPH has been done in our article. NPH is an important cause of potentially reversible dementia, frequent falls, and recurrent urinary infections in the elderly. The clinical and imaging features of NPH may be incomplete or nonspecific, posing a diagnostic challenge for medical doctors, and often requiring expert assessment to minimize unsuccessful surgical treatments. Recent advances resulting from the use of noninvasive magnetic resonance imaging methods for quantifying cerebral blood flow, in particular arterial spin-labeling, and the frequent association of NPH and obstructive sleep apnea, offer new avenues to understand and treat NPH. |
| Databáze: | OpenAIRE |
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