Common medium versus advanced IVF medium for cryopreserved oocytes in heterologous cycles
| Autor: | W Bielli, R. Lisi, A Costantino, F. Lisi, P Carfagna, G. Nicodemo, D. Iacomino, R. Poverini, V Berlinghieri |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Cancer Research 030219 obstetrics & reproductive medicine lcsh:Cytology Immunology Embryogenesis Heterologous Embryo Cell Biology Biology lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens lcsh:RC254-282 Article Cryopreservation Andrology 03 medical and health sciences Cellular and Molecular Neuroscience Pregnancy rate 030104 developmental biology 0302 clinical medicine Human fertilization embryonic structures IVF medium lcsh:QH573-671 Embryo quality |
| Zdroj: | Cell Death Discovery, Vol 4, Iss 1, Pp 1-4 (2018) Cell Death Discovery |
| ISSN: | 2058-7716 |
| DOI: | 10.1038/s41420-017-0025-2 |
| Popis: | Granulocyte-macrophage colony-stimulation factor plays different crucial roles during embryo implantation and subsequent development. Here we aimed to evaluate the effects of embryo cell culture medium, with the inclusion of granulocyte-macrophage colony-stimulation factor (GM-CSF), on embryo development and pregnancy rate. To this end, we took advantage of our retrospective observational study to correlate the outcomes from two different culture media. We included in this study 25 unselected patient from our IVF Center that underwent heterologous IVF cycle with crypreserved oocytes. We analyze the fertilization rate, pregnancy rate, and embryo quality at different day of transfer obtained from two different media composition. Our results show that the rate of fertilization and the pregnancy rate were increased using medium added with this particular type of cytokines (GM-CSF). |
| Databáze: | OpenAIRE |
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