Dedifferentiated chondrosarcoma of the appendicular skeleton: MRI-pathological correlation
| Autor: | Fergus MacSweeney, Asif Saifuddin, Alan J Darby |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Male
musculoskeletal diseases Osteochondroma medicine.medical_specialty Pathology animal structures Appendicular skeleton Biopsy Statistics as Topic Chondrosarcoma Bone Neoplasms Diagnosis Differential Calcification Physiologic London medicine Humans Radiology Nuclear Medicine and imaging Femur Aged Neoplasm Staging Retrospective Studies Tibia medicine.diagnostic_test business.industry Cartilage digestive oral and skin physiology Magnetic resonance imaging Anatomical pathology Anatomy Humerus Middle Aged musculoskeletal system medicine.disease Magnetic Resonance Imaging medicine.anatomical_structure embryonic structures Female Sarcoma Tomography X-Ray Computed business Calcification |
| Zdroj: | Skeletal Radiology. 32:671-678 |
| ISSN: | 1432-2161 0364-2348 |
| DOI: | 10.1007/s00256-003-0706-1 |
| Popis: | To correlate the T2-weighted and STIR MRI appearances of dedifferentiated appendicular chondrosarcoma with gross and microscopic pathology.Nine patients with a histologically confirmed diagnosis of dedifferentiated appendicular chondrosarcoma were identified from the Bone Tumour Registry. All patients underwent MRI, including T2-weighted and/or STIR sequences in at least one plane, prior to limb salvage surgery. Areas of reduced signal intensity (SI) compared with hyperintense chondral tumour on the T2-weighted or STIR images were correlated with the resection specimen, to determine the relationship of such out areas of reduced SI with regions of dedifferentiation.Patients presented over a period of 7 years. There were five men and four women with mean age 68.2 years and age range 51-78 years. Tumours arose in the femur (6 cases), humerus (2 cases) and tibia (1 case). Three MRI patterns were identified: (1) type 1, a lesion with two distinct signal characteristics-hyperintense chondral and reduced SI dedifferentiated tumour (n=6); type 2, mainly reduced SI lesion-dedifferentiated tumour, with areas of signal void corresponding to matrix calcification (n=2); type 3, a heterogeneous lesion with no radiological evidence of underlying chondral tumour (n=1). T2-weighted or STIR MR sequences can identify areas of dedifferentiation, which should be the preferential site of pre-operative biopsy. |
| Databáze: | OpenAIRE |
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