Corynebacterium Jeikeium Endocarditis: A Review of the Literature
| Autor: | Marc Y. El Khoury, Wilbert S. Aronow, Purva Ranchal, Rahul Gupta, Jagjit Khosla, William H. Frishman, Tarun Popli |
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| Rok vydání: | 2020 |
| Předmět: |
biology
Corynebacterium Infections medicine.drug_class business.industry medicine.medical_treatment Cephalosporin Corynebacterium General Medicine Endocarditis Bacterial medicine.disease biology.organism_classification Microbiology Anti-Bacterial Agents Penicillin Valve replacement Corynebacterium jeikeium Infective endocarditis Skin surface medicine Endocarditis Humans Cardiology and Cardiovascular Medicine business medicine.drug |
| Zdroj: | Cardiology in review. 29(5) |
| ISSN: | 1538-4683 |
| Popis: | Corynebacterium jeikeium is a gram-positive, aerobic, pleomorphic, non-spore forming bacillus, commonly present on the skin surface. Infective endocarditis secondary to C. jeikeium most commonly affects left-sided heart valves and has a higher likelihood to require valve replacement compared to other Corynebacterium endocarditis. C. jeikeium endocarditis is extremely difficult to treat as it is characteristically resistant to penicillin, cephalosporins and aminoglycosides, and sensitivity to quinolones, macrolides, tetracyclines and rifampin is variable. Despite treatment, mortality rates as high as 33% have been reported. We hereby review the literature regarding the epidemiology, diagnosis and treatment of this deadly microorganism. |
| Databáze: | OpenAIRE |
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