Dietary fat and breast cancer risk in the Swedish women's lifestyle and health cohort

Autor: Elisabete Weiderpass, Sven Sandin, Marie Löf, Leena Hilakivi-Clarke, Pagona Lagiou, Hans-Olov Adami, Dimitrios Trichopoulos
Jazyk: angličtina
Rok vydání: 2007
Předmět:
Cancer Research
saturated fat
Epidemiology
Saturated fat
Health Status
Physiology
Cohort Studies
Fatty Acids
Monounsaturated
Polyunsaturated fat
Risk Factors
Surveys and Questionnaires
Poisson Distribution
Prospective Studies
Registries
Prospective cohort study
polyunsaturated fat
food and beverages
cohort
Middle Aged
Oncology
Receptors
Estrogen
Cohort
Fatty Acids
Unsaturated
lipids (amino acids
peptides
and proteins)
Female
Receptors
Progesterone
Cohort study
Adult
medicine.medical_specialty
Breast Neoplasms
monounsaturated fat
Diet Surveys
Breast cancer
breast cancer
Dietary Fats
Unsaturated
Internal medicine
medicine
Humans
Risk factor
Life Style
Proportional Hazards Models
Sweden
business.industry
Cancer
medicine.disease
Dietary Fats
Endocrinology
total dietary fat
business
Follow-Up Studies
Zdroj: British Journal of Cancer
ISSN: 1532-1827
0007-0920
Popis: We investigated whether dietary intakes of total fat, monounsaturated fat (MUFA), polyunsaturated fat (PUFA) and saturated fat (SFA) were associated with breast cancer risk in a prospective cohort of 49 261 Swedish women (30–49 years at enrolment), which yielded 974 breast cancer cases by December 2005. Further, we evaluated if associations differed by oestrogen and/or progesterone receptor tumour status. Total fat, MUFA, PUFA or SFA were not associated with risk overall. However, women in the highest MUFA and PUFA quintile intake had a reduced breast cancer risk after age 50 years (hazard ratios: 95% confidence interval=0.45: 0.25–0.99 and 0.54: 0.35–0.85, respectively) compared to women in the lowest quintile. The associations did not differ by oestrogen or progesterone receptor status. Despite the negative findings, type of fat during premenopausal years may have later differential effects on risk.
Databáze: OpenAIRE
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