Serotonin in retina
Autor: | Justine Masson |
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Přispěvatelé: | CCSD, Accord Elsevier, Institut de psychiatrie et neurosciences (U894 / UMS 1266), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM) |
Jazyk: | angličtina |
Rok vydání: | 2019 |
Předmět: |
0301 basic medicine
Serotonin MESH: Receptors Serotonin [SDV]Life Sciences [q-bio] Biochemistry Retina 03 medical and health sciences chemistry.chemical_compound medicine Animals Humans MESH: Animals Receptor 5-HT receptor MESH: Humans 030102 biochemistry & molecular biology Chemistry MESH: Retina Retinal General Medicine Pathophysiology Cell biology Vesicular monoamine transporter [SDV] Life Sciences [q-bio] 030104 developmental biology medicine.anatomical_structure Receptors Serotonin MESH: Serotonin Signal transduction |
Zdroj: | Biochimie Biochimie, Elsevier, 2019, 161, pp.51-55. ⟨10.1016/j.biochi.2018.11.006⟩ |
ISSN: | 0300-9084 |
DOI: | 10.1016/j.biochi.2018.11.006 |
Popis: | International audience; The expression of serotonin (5-HT) in the retina was first reported in the sixties. The detection of vesicular monoamine transporter and serotonin receptors in several retinal cells confirm that 5-HT is playing a neuromodulatory role in this structure. Whereas signaling pathways activated by 5-HT receptor binding has been poorly investigated so far, numerous data demonstrated that 5-HT is involved in retinal physiology, retinal physiopathology and photoreceptor survival. |
Databáze: | OpenAIRE |
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