Photothermal spectro-microscopy as benchmark for optoplasmonic bio-detection assays
Autor: | Subhasis Adhikari, Patrick Spaeth, Martin D. Baaske, Nasrin Asgari, Michel Orrit, Deep Punj |
---|---|
Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Analyte
Nanostructure Materials science Nanotechnology 02 engineering and technology Photothermal therapy 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences Article 0104 chemical sciences Surfaces Coatings and Films Electronic Optical and Magnetic Materials Characterization (materials science) General Energy Microscopy Benchmark (computing) Physical and Theoretical Chemistry 0210 nano-technology Plasmonic nanostructures Nanoscopic scale |
Zdroj: | The Journal of Physical Chemistry. C, Nanomaterials and Interfaces The Journal of Physical Chemistry C, 125(45), 25087–25093 |
Popis: | Optoplasmonic bio-detection assays commonly probe the response of plasmonic nanostructures to changes in their dielectric environment. The accurate detection of nanoscale entities such as virus particles, micelles and proteins requires optimization of multiple experimental parameters. Performing such optimization directly via analyte recognition is often not desirable or feasible, especially if the nanostructures exhibit limited numbers of analyte binding sites and if binding is irreversible. Here we introduce photothermal spectro-microscopy as a benchmarking tool for the characterization and optimization of optoplasmonic detection assays. |
Databáze: | OpenAIRE |
Externí odkaz: |