Minireview: The Introduction of COVID-19 and Microvascular Disease-Introduction of COVID-19 and the Relationship between Its Receptor and Diabetic Vascular Complications
| Autor: | Qi-Zhuang Ma, Pei-Yao Lin, Xu-Li Fan, Dong-Xu Qin, Dongze Lu, Ying Song |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Coronavirus disease 2019 (COVID-19) Critical Illness MEDLINE Disease medicine.disease_cause Kidney Cardiovascular System Diabetes mellitus Epidemiology Genetics Medicine Humans Intensive care medicine Receptor Molecular Biology Coronavirus Diabetic Retinopathy business.industry Vascular disease SARS-CoV-2 COVID-19 medicine.disease Host-Pathogen Interactions Angiotensin-Converting Enzyme 2 business Diabetic Angiopathies |
| Zdroj: | Critical reviews in eukaryotic gene expression. 30(6) |
| ISSN: | 1045-4403 |
| Popis: | In December of 2019, a novel coronavirus, which is SARS-CoV-2, broke out in the world and caused tremendous human and financial losses. According to a descriptive study by the relative hospital about the epidemiological and clinical features of 52 critically ill patients, the expert panel found that people with cardiovascular disease and diabetes comprise a large proportion of the patients with chronic disease. In this review, we discuss the structural biology of the SARS-CoV-2 in combination with the characteristics of its binding protein, ACE2, which is an important receptor in the cardiovascular system and may have potential relationships with various diabetic diseases. We hope we can provide useful recommendations for patients with diabetes after becoming infected by the virus or provide directions to doctors on treatment options. |
| Databáze: | OpenAIRE |
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