The association between gait variability with the energy cost of walking depends on the fall status in people with multiple sclerosis without mobility aids
| Autor: | Alon Kalron, Uri Givon, Lior Frid, Shay Menascu |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Multiple Sclerosis Correlation coefficient Cross-sectional study Population Biophysics Walking 03 medical and health sciences 0302 clinical medicine Physical medicine and rehabilitation Gait (human) Humans Medicine Orthopedics and Sports Medicine Association (psychology) education Gait education.field_of_study business.industry Multiple sclerosis Rehabilitation 030229 sport sciences Middle Aged medicine.disease Cross-Sectional Studies Italy Exercise Test Energy cost Accidental Falls Female Analysis of variance business human activities 030217 neurology & neurosurgery |
| Zdroj: | Gait & Posture. 74:231-235 |
| ISSN: | 0966-6362 |
| Popis: | Background Falls, gait variability and increased energy cost of walking are common in people with multiple sclerosis (PwMS). However, no studies have as yet examined this triple association in PwMS or in other neurological populations. Research question Does a relationship exist between gait variability, falls and the energy cost of gait in PwMS? Methods This cross sectional study included 88 PwMS (50 women), mean age 39.8 (S.D = 13.0) and mean disease duration of 6.2 (SD = 8.2) years since diagnosis. Energy expenditure during walking was collected via a portable metabolic device (COSMED K5, COSMED Srl, Roma, Italy). Gait variability was measured by an electronic walkway (GAITRite™). Participants were divided into groups based on fall history (fallers and non-fallers). Differences between groups in terms of energy expenditure measures and gait variability metrics were determined by the analysis of variance test. The relationship between gait variability and energy cost of walking was examined by the Pearson's correlation coefficient test. Results Thirty-three PwMS were classified as fallers and 55 as non-fallers. Non-significant differences between groups were observed in the energy expenditure measures, including cost of walking. Fallers demonstrated higher step length variability compared with non-fallers (4.58 (S.D. = 2.42 vs. 3.40 (S.D. = 1.40); p-value = 0.005). According to the Pearson's correlation coefficient analysis, a significant relationship was found between step length variability and energy cost of walking in the non-fallers group (Rho = 0.372, P-value = 0.006) and the total group (Rho = 0.296, p-value = 0.005), but not in those PwMS with a history of falls. Significance We demonstrated a significant relationship between increased gait variability and energy expenditure while walking only in MS patients without a history of falls. This is important as there is evidence of the clinical relevance of increased gait variability, poor fitness level and high risk of falling in the MS population. |
| Databáze: | OpenAIRE |
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