Nonlinear stress relaxation of transiently crosslinked biopolymer networks
| Autor: | Chase P. Broedersz, Tomer Markovich, Fred C. MacKintosh, Sihan Chen |
|---|---|
| Přispěvatelé: | Physics of Living Systems, LaserLaB - Energy, Physics and Astronomy |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0303 health sciences
Work (thermodynamics) Materials science FOS: Physical sciences engineering.material Condensed Matter - Soft Condensed Matter 01 natural sciences 03 medical and health sciences Nonlinear system Rheology Biological Physics (physics.bio-ph) 0103 physical sciences engineering Molecular motor Biophysics Stress relaxation Soft Condensed Matter (cond-mat.soft) Biopolymer Transient (oscillation) Physics - Biological Physics 010306 general physics Cytoskeleton 030304 developmental biology |
| Zdroj: | Chen, S, Broedersz, C P, Markovich, T & MacKintosh, F C 2021, ' Nonlinear stress relaxation of transiently crosslinked biopolymer networks ', Physical review E, vol. 104, no. 3, 034418, pp. 1-14 . https://doi.org/10.1103/PhysRevE.104.034418 Physical review E, 104(3):034418, 1-14. American Physical Society |
| ISSN: | 2470-0053 2470-0045 |
| DOI: | 10.1103/PhysRevE.104.034418 |
| Popis: | A long-standing puzzle in the rheology of living cells is the origin of the experimentally observed long-time stress relaxation. The mechanics of the cell is largely dictated by the cytoskeleton, which is a biopolymer network consisting of transient crosslinkers, allowing for stress relaxation over time. Moreover, these networks are internally stressed due to the presence of molecular motors. In this work we propose a theoretical model that uses a mode-dependent mobility to describe the stress relaxation of such prestressed transient networks. Our theoretical predictions agree favorably with experimental data of reconstituted cytoskeletal networks and may provide an explanation for the slow stress relaxation observed in cells. |
| Databáze: | OpenAIRE |
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