Birth of healthy children after intracytoplasmic sperm injection in two couples with male Kartagener’s syndrome
| Autor: | Hermann-Josef Vogt, Annette von Zumbusch, Artur Mayerhofer, Johannes Ring, Klaus Fiedler, Berthold Jeßberger |
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| Rok vydání: | 1998 |
| Předmět: |
Adult
Male Infertility Cytoplasm medicine.medical_specialty Microinjections Offspring medicine.medical_treatment Reproductive medicine Intracytoplasmic sperm injection Human reproduction Reproductive Techniques Pregnancy medicine Humans Infertility Male reproductive and urinary physiology Gynecology S syndrome Kartagener Syndrome urogenital system business.industry Pregnancy Outcome Obstetrics and Gynecology medicine.disease Situs inversus Reproductive Medicine Female business |
| Zdroj: | Fertility and Sterility. 70:643-646 |
| ISSN: | 0015-0282 |
| Popis: | Objective: To describe two cases in which intracytoplasmic sperm injection (ICSI) was successful for patients with infertility due to Kartagener's syndrome. Design: Case report. Setting: Private hospital for gynecology department of reproductive medicine, and university hospital center for andrology. Patient(s): Two couples with primary infertility due to Kartagener's syndrome in the male. Intervention(s): ICSI. Main Outcome Measure(s): Pregnancy and birth after ICSI. Result(s): In both couples, ICSI was successful in the first cycle. The uncomplicated pregnancies resulted in the birth of three healthy children. One female and male/female twins. Conclusion(s): In couples with infertility due to Kartagener's syndrome in the male, ICSI has proved to be a successful therapy resulting in clinically healthy offspring. This knowledge may improve our understanding of the involvement of paternally inherited centrosomes, which nucleate microtubules, in human reproduction. |
| Databáze: | OpenAIRE |
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