A double-blind placebo controlled trial on effectiveness of prophylactic dexamethasone for preventing post- dural puncture headache after spinal anesthesia for cesarean section
| Autor: | Joseph I Ikechebelu, Toochukwu Benjamin Ejikeme, Boniface Chukwuneme Okpala, George Uchenna Eleje, Augusta Okpala, Cyril Emeka Nwachukwu, Chukwuemeka Jude Ofojebe |
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| Rok vydání: | 2020 |
| Předmět: |
Post-dural-puncture headache
Placebo-controlled study Placebo Anesthesia Spinal Spinal Puncture Dexamethasone law.invention Double blind 03 medical and health sciences 0302 clinical medicine Randomized controlled trial Double-Blind Method law Pregnancy Medicine Humans business.industry Cesarean Section Obstetrics and Gynecology Spinal anesthesia Nausea 030220 oncology & carcinogenesis Anesthesia Pediatrics Perinatology and Child Health 030211 gastroenterology & hepatology Female medicine.symptom Post-Dural Puncture Headache business medicine.drug |
| Zdroj: | The journal of maternal-fetalneonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians. 35(17) |
| ISSN: | 1476-4954 |
| Popis: | To determine the effect of dexamethasone in reducing post-dural puncture headache (PDPH) after spinal anesthesia for cesarean section (CS).A double blind placebo controlled randomized trial of parturients undergoing CS under spinal anesthesia was conducted. Participants (Baseline socio-demographic and clinical variables were similar between the two groups and none of the women was lost to follow up. The incidence of PDPH (8.3% vs 25.0%;Prophylactic dexamethasone reduces the incidence and severity of PDPH on both the first and fourth post-operative day after spinal anesthesia for CS. There was also an improvement on the incidence of nausea on the dexamethasone group compared to control. |
| Databáze: | OpenAIRE |
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