POLAR Registry (Promus eluting stent registry in Latin America): 1 year Follow-up Results
| Autor: | Marco Antonio Perin, Flavio Passos Barbosa, J. Ribamar Costa, Alexandre Abizaid, Cristiano Freitas de Souza, José Airton de Arruda, José Armando Mangione, Renato Giestas Serpa, Rogério Sarmento-Leite, Fausto Feres, Décio Salvadori, Andrea Abizaid, Esmeralci Ferreira, Costantino R. Costantini |
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| Rok vydání: | 2012 |
| Předmět: |
medicine.medical_specialty
Acute coronary syndrome Coronary restenosis medicine.medical_treatment 1 year follow up Stents farmacológicos Lesion Coronary thrombosis medicine Adverse effect Drug-eluting stents Reestenose coronária Everolimus Trombose coronária business.industry Stent General Medicine medicine.disease Thrombosis Surgery Radiology medicine.symptom business Cardiology and Cardiovascular Medicine medicine.drug |
| Zdroj: | Revista Brasileira de Cardiologia Invasiva English Version. 20(1):29-34 |
| ISSN: | 0104-1843 |
| DOI: | 10.1016/s0104-1843(12)50007-x |
| Popis: | BACKGROUNDDrug-eluting stents have been used since 2002 in different patient populations aiming to achieve high success rates with low clinical and angiographic restenosis rates. With the late thrombosis adverse events associated to the first generation sirolimus and paclitaxel-eluting stents, second-generation everolimus and zotarolimus-eluting stents has been recently developed.METHODSThe POLAR registry is a prospective, non-randomized, multicenter study, which included 988 patients, totaling 1,362 lesions treated with the everolimus-eluting stent Promus®. In order to represent the clinical practice, almost all subtypes of patients and lesions were included in this registry. Clinical follow-up was planned to be performed 1, 6, 12 and 24 months after the procedure.RESULTSMost patients were male (69.8%), with mean age of 64.9±9.4years, 35.2% were diabetics and 55% had been treated for acute coronary syndrome. Vessel diameter was 2.95±0.43mm and lesion extension was 20.5±5.6mm. A total of 1.14±0.38 stent/patient were implanted and the procedural success rate was 96.6%. Major adverse cardiac events occurred in 4.5% of patients, and stent thrombosis was observed in 5 patients (0.5%) after a clinical follow-up of 12 months.CONCLUSIONSThe present registry suggests that everolimus-eluting stents are safe and effective in daily clinical practice patients, with a low rate of major adverse cardiac events at the end of the first year of follow-up. |
| Databáze: | OpenAIRE |
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