Adaptive walks and extreme value theory

Autor: Johannes Neidhart, Joachim Krug
Rok vydání: 2011
Předmět:
DOI: 10.48550/arxiv.1105.0592
Popis: We study biological evolution in a high-dimensional genotype space in the regime of rare mutations and strong selection. The population performs an uphill walk which terminates at local fitness maxima. Assigning fitness randomly to genotypes, we show that the mean walk length is logarithmic in the number of initially available beneficial mutations, with a prefactor determined by the tail of the fitness distribution. This result is derived analytically in a simplified setting where the mutational neighborhood is fixed during the adaptive process, and confirmed by numerical simulations.
Comment: 4 pages, 2 figures; final version, to appear in Physical Review Letters
Databáze: OpenAIRE