Immersive Virtual Reality and Ocular Tracking for Brain Mapping During Awake Surgery: Prospective Evaluation Study

Autor: Gwénaëlle Soulard, Ghislaine Aubin, Matthieu Delion, Anne Clavreul, Philippe Menei, Morgane Casanova, Renaud Seguier, Aram Ter Minassian
Přispěvatelé: CentraleSupélec, Département de neurochirurgie [Angers], Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM)-PRES Université Nantes Angers Le Mans (UNAM), Design and Application of Innovative Local Treatments in Glioblastoma (CRCINA-ÉQUIPE 17), Centre de Recherche en Cancérologie et Immunologie Nantes-Angers (CRCINA), Université d'Angers (UA)-Université de Nantes (UN)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre hospitalier universitaire de Nantes (CHU Nantes)-Université d'Angers (UA)-Université de Nantes (UN)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre hospitalier universitaire de Nantes (CHU Nantes), PRES Université Nantes Angers Le Mans (UNAM), Fondation de l’Avenir, Paris, France (AP-RM 18-032)Angers University Hospital, Clavreul, Anne, Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-Centre hospitalier universitaire de Nantes (CHU Nantes)-Centre National de la Recherche Scientifique (CNRS)-Université d'Angers (UA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-Centre hospitalier universitaire de Nantes (CHU Nantes)-Centre National de la Recherche Scientifique (CNRS)-Université d'Angers (UA)
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Male
medicine.medical_specialty
Headset
Health Informatics
[SDV.CAN]Life Sciences [q-bio]/Cancer
nonverbal language
Virtual reality
computer.software_genre
lcsh:Computer applications to medicine. Medical informatics
visuospatial cognition
Brain mapping
eye tracking
03 medical and health sciences
Nonverbal communication
0302 clinical medicine
Physical medicine and rehabilitation
[SDV.CAN] Life Sciences [q-bio]/Cancer
medicine
Humans
Prospective Studies
Wakefulness
Original Paper
Facial expression
mobile phone
Brain Neoplasms
lcsh:Public aspects of medicine
[SCCO.NEUR]Cognitive science/Neuroscience
[SCCO.NEUR] Cognitive science/Neuroscience
Cognition
lcsh:RA1-1270
awake surgery
Virtual machine
030220 oncology & carcinogenesis
Eye tracking
lcsh:R858-859.7
virtual reality
brain mapping
Female
Psychology
computer
030217 neurology & neurosurgery
Zdroj: Journal of Medical Internet Research
Journal of Medical Internet Research, 2021, 23 (3), pp.e24373. ⟨10.2196/24373⟩
Journal of Medical Internet Research, Vol 23, Iss 3, p e24373 (2021)
Journal of Medical Internet Research, JMIR Publications, 2021, 23 (3), pp.e24373. ⟨10.2196/24373⟩
ISSN: 1438-8871
Popis: Background Language mapping during awake brain surgery is currently a standard procedure. However, mapping is rarely performed for other cognitive functions that are important for social interaction, such as visuospatial cognition and nonverbal language, including facial expressions and eye gaze. The main reason for this omission is the lack of tasks that are fully compatible with the restrictive environment of an operating room and awake brain surgery procedures. Objective This study aims to evaluate the feasibility and safety of a virtual reality headset equipped with an eye-tracking device that is able to promote an immersive visuospatial and social virtual reality (VR) experience for patients undergoing awake craniotomy. Methods We recruited 15 patients with brain tumors near language and/or motor areas. Language mapping was performed with a naming task, DO 80, presented on a computer tablet and then in 2D and 3D via the VRH. Patients were also immersed in a visuospatial and social VR experience. Results None of the patients experienced VR sickness, whereas 2 patients had an intraoperative focal seizure without consequence; there was no reason to attribute these seizures to virtual reality headset use. The patients were able to perform the VR tasks. Eye tracking was functional, enabling the medical team to analyze the patients’ attention and exploration of the visual field of the virtual reality headset directly. Conclusions We found that it is possible and safe to immerse the patient in an interactive virtual environment during awake brain surgery, paving the way for new VR-based brain mapping procedures. Trial Registration ClinicalTrials.gov NCT03010943; https://clinicaltrials.gov/ct2/show/NCT03010943.
Databáze: OpenAIRE