Mild chronic anemia following heart transplantation: a syndrome with prognostic relevance?
| Autor: | Reingard Aigner, B. Petutschnigg, T. Allmayer, Andre Wasler, Jörg H. Horina, Barbara Grasser, Peter Rehak, Günter Prenner, H. Müller, Silvia Schaffellner, Karlheinz Tscheliessnigg, Thomas Lang, Florian Iberer |
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| Rok vydání: | 1998 |
| Předmět: |
Adult
Male Nephrology medicine.medical_specialty Adolescent Anemia Iron medicine.medical_treatment Hematocrit Gastroenterology hemic and lymphatic diseases Internal medicine medicine Humans Erythropoietin Survival rate Aged Heart transplantation Transplantation Hematology medicine.diagnostic_test business.industry Middle Aged Prognosis medicine.disease Surgery Survival Rate Chronic Disease Heart Transplantation Female Morbidity business medicine.drug |
| Zdroj: | Transplant International. 11:413-418 |
| ISSN: | 1432-2277 0934-0874 |
| DOI: | 10.1111/j.1432-2277.1998.tb00829.x |
| Popis: | The clinical relevance of mild chronic anemia in patients after heart transplantation (HTX) has not yet been demonstrated. Forty-five outpatients who had undergone HTX 2–99 months prior to investigation and who had not received blood transfusions or erythropoietin (EPO) before data acquisition were observed over a period of 37 months. Anemia was found in 36 of the 45 patients and was normocytic, normochromic, and slightly anisocytotic (coefficient of variation = 16 ± 2, normal 11.5–14.5). Anemic patients showed elevated EPO levels, whereas in nonanemic patients EPO levels were normal. Survival after HTX differed significantly in anemic and nonanemic patients (P < 0.02), with 100 % survival in the nonanemic and 85 % in the anemic group. Chronic anemia in patients after HTX shows a typical pattern. Even when mild, anemia in patients after HTX seems to be of prognostic value and thus might be an indicator of chronic disorders. |
| Databáze: | OpenAIRE |
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