Association of microalbuminuria with metabolic syndrome: a cross-sectional study in Bangladesh
| Autor: | Manindra Nath Roy, Rubena Haque, Muntakim Mahmud Saadi, Shakil Mahmood, Farida Akhter Tania, Nurshad Ali |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Cross-sectional study Endocrinology Diabetes and Metabolism lcsh:Diseases of the endocrine glands. Clinical endocrinology Body Mass Index Young Adult Risk Factors Internal medicine Diabetes mellitus Bangladeshi adults medicine Prevalence Albuminuria Humans National Cholesterol Education Program Bangladesh lcsh:RC648-665 medicine.diagnostic_test business.industry General Medicine Middle Aged medicine.disease Prognosis Metabolic syndrome Blood pressure Cross-Sectional Studies Microalbuminuria Female Lipid profile business Body mass index Biomarkers Follow-Up Studies Research Article |
| Zdroj: | BMC Endocrine Disorders, Vol 20, Iss 1, Pp 1-7 (2020) BMC Endocrine Disorders |
| ISSN: | 1472-6823 |
| DOI: | 10.1186/s12902-020-00634-0 |
| Popis: | Background and aims The objectives of this study were to estimate the prevalence of microalbuminuria and examine the association of microalbuminuria with metabolic syndrome (MetS) and its component in a Bangladeshi adult cohort. Methods This cross-sectional study included 175 subjects (84 males and 91 females; aged 19–59 years), recruited from the outdoor Department of Medicine and Endocrinology of a medical college hospital in Dhaka, Bangladesh. Lipid profile and fasting blood glucose (FBG) were measured in serum and albumin and creatinine were determined in urine samples. Microalbuminuria was defined as the urinary albumin-to-creatinine ratio (ACR) of 30 to 300 mg/g. The MetS was defined according to the criteria of the National Cholesterol Education Program (NECP). The association of microalbuminuria with MetS and its components was evaluated by multivariate logistic regression analysis. Results Among the study subjects, 66.3% were hypertensive and 70.3% were diabetic individuals. Overall, the prevalence of microalbuminuria was 29.7% with 31% in males and 28.6% in females. Microalbuminuria was 2.6 fold higher in hypertensive and diabetic adults than in the non-hypertensive or non-diabetic adults. The prevalence of microalbuminuria was much more frequent in persons with the MetS (36.0%) than the persons without the MetS (5.4%). The levels of FBG, systolic blood pressure (SBP), diastolic blood pressure (DBP) and triglycerides were significantly higher (p p Conclusions Microalbuminuria was strongly associated with MetS in Bangladeshi adults. Elevated BP and FBG were the most predominant components of MetS among the study subjects. Comprehensive management of MetS at its early stage can be effective to prevent and reduce the progression of kidney injury and cardiovascular complications. |
| Databáze: | OpenAIRE |
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