Cerebral hemodynamics on near-infrared spectroscopy in hypoxia and ischemia in young animal studies
| Autor: | Hirofumi Kimoto, Satoshi Kamei, Satoru Hirano, Motohiro Hasegawa, Sachio Takashima |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
medicine.medical_specialty
Spectrophotometry Infrared Nitrogen Ischemia Biology Hypoglycemia Brain Ischemia Electron Transport Complex IV Hemoglobins Adenosine Triphosphate Oxygen Consumption Developmental Neuroscience Internal medicine Hyperventilation medicine Animals Cytochrome c oxidase Hypoxia Brain Brain Chemistry General Medicine Oxygenation Carbon Dioxide Hypoxia (medical) medicine.disease Endocrinology Cerebrovascular Circulation Pediatrics Perinatology and Child Health biology.protein Rabbits Neurology (clinical) Hemoglobin Blood Gas Analysis Cytochrome aa3 medicine.symptom |
| Zdroj: | Brain and Development. 17:312-316 |
| ISSN: | 0387-7604 |
| Popis: | Using near-infrared spectroscopy the changes of intracranial oxyhemoglobin, deoxyhemoglobin, total hemoglobin and cytochrome aa3, which show the progression of intracranial oxygenation, hemodynamics and cell metabolism, were recorded during prolonged partial hypoxia induced by carbon dioxide (CO2) and nitrogen (N2), ischemia induced by hyperventilation, and hypoxia during hypoglycemia in neonatal and young rabbits. The reduction of cytochrome aa3 during the terminal stage of CO2-induced prolonged hypoxia, hyperventilation and hypoxia in hypoglycemia suggests that the redox state of cytochrome aa3 will be changed by several combined factors such as oxygen delivery, ATP demand and substrate (glucose) delivery. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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