Cohort profile: the Prospective Research In Stress-Related Military Operations (PRISMO) study in the Dutch Armed Forces
| Autor: | Sija J. van der Wal, Alieke Reijnen, Eric Vermetten, Rosalie Gorter, Elbert Geuze |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Sleep Wake Disorders Gerontology Population Sample (statistics) Anxiety Representativeness heuristic Stress Disorders Post-Traumatic Young Adult 03 medical and health sciences 0302 clinical medicine Prevalence Journal Article Humans risk factors Medicine Longitudinal Studies Prospective Studies education Netherlands Combat Disorders education.field_of_study Cohort Profile Afghan Campaign 2001 Depression business.industry Afghanistan military cohort General Medicine Middle Aged Mental health 030227 psychiatry Military personnel Mental Health Military Personnel Software deployment Cohort Female business 030217 neurology & neurosurgery Military deployment |
| Zdroj: | BMJ Open, 9(3). BMJ PUBLISHING GROUP BMJ Open BMJ Open, 9(3). BMJ Publishing Group |
| ISSN: | 2044-6055 |
| Popis: | PurposeThe Prospective Research in Stress-Related Military Operations (PRISMO) study was initiated to gain a better understanding of the long-term impact of military deployment on mental health, and to map the different biological and psychological factors that contribute to the development of stress-related mental health symptoms.ParticipantsThe PRISMO cohort consists of a convenience sample of Dutch military personnel deployed to Afghanistan between 2005 and 2008. Baseline data collection resulted in the recruitment of 1032 military men and women. Combat troops as well as non-combat support troops were recruited to increase the representativeness of the sample to the population as a whole.Findings to dateThe prevalence of various mental health symptoms increases after deployment in PRISMO cohort members, but symptom progression over time appears to be specific for various mental health symptoms. For post-traumatic stress disorder, we found a short-term symptom increase within 6 months after deployment (8.2%), and a long-term symptom increase at 5 years after deployment (12.9%). Several biological vulnerability factors associated with the development of stress-related conditions after deployment were identified, including predeployment glucocorticoid receptor sensitivity and predeployment testosterone level. Thus far, 34 publications have resulted from the cohort.Future plansVarious analyses are planned that will include the prevalence of mental health symptoms at 10 years postdeployment, as well as trajectory analyses that capture the longitudinal development of symptoms. Furthermore, we will use a machine learning approach to develop predictive and network models for several mental health symptoms, incorporating biological, psychological and social factors. |
| Databáze: | OpenAIRE |
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