Characterization of the synthetic biology-inspired implementation of a materials-based positive feedback loop
| Autor: | Jens Timmer, Raphael Engesser, Christian Geraths, Hanna J. Wagner, Wilfried Weber, Kathrin Ermes |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0106 biological sciences
0301 basic medicine Stimuli responsive Computer science Smart material lcsh:Computer applications to medicine. Medical informatics 01 natural sciences 03 medical and health sciences Synthetic biology 010608 biotechnology Research article Signal amplification lcsh:Science (General) Positive feedback Proteomics and Biochemistry Stimulus-responsive Multidisciplinary Smart materials Control engineering Characterization (materials science) Protease 030104 developmental biology Systems design lcsh:R858-859.7 lcsh:Q1-390 Information-processing |
| Zdroj: | Data in Brief Data in Brief, Vol 19, Iss, Pp 665-677 (2018) |
| ISSN: | 2352-3409 |
| Popis: | The translation of engineering designs to materials sciences by means of synthetic biological tools represents a novel concept for the development of information-processing materials systems. Here, we provide data on the mathematical model-guided implementation of a biomaterials-based positive feedback loop for the detection of proteolytic activities. Furthermore, we present data on an extended system design for the detection of the antibiotic novobiocin.This work is related to the research article “Synthetic biology-inspired design of signal-amplifying materials systems” (Wagner et al., 2018) [1]. Keywords: Information-processing, Protease, Signal amplification, Smart materials, Stimulus-responsive |
| Databáze: | OpenAIRE |
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