Hypolipidemic activity of three indigenous drugs in experimentally induced atherosclerosis
| Autor: | S. L. Udupa, A. L. Udupa, H. P. Shaila |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Male
Pathology medicine.medical_specialty Arteriosclerosis medicine.medical_treatment Pharmacology Cholesterol Dietary chemistry.chemical_compound medicine.artery Hyperlipidemia Animals Medicine Aorta Abdominal Aspartate Aminotransferases Phospholipids Triglycerides Hypolipidemic Agents Aorta Chemotherapy Plants Medicinal Lagomorpha biology business.industry Cholesterol Myocardium Alanine Transaminase Alkaline Phosphatase biology.organism_classification medicine.disease Lipids Medicine Ayurvedic Partial inhibition Treatment Outcome Atheroma Liver chemistry Rabbits Terminalia arjuna Cardiology and Cardiovascular Medicine business |
| Zdroj: | International Journal of Cardiology. 67:119-124 |
| ISSN: | 0167-5273 |
| DOI: | 10.1016/s0167-5273(98)00281-2 |
| Popis: | The effect of orally administered indigenous drugs Terminalia arjuna, T. belerica and T. chebula were investigated on experimental atherosclerosis. Rabbits were fed a cholesterol-rich diet to induce atherosclerosis. The three drugs were fed along with cholesterol. At the end of the experimental period the animals were killed and their plasma and tissue lipid components estimated. Atherosclerotic lesions of the aorta were examined histologically. T. arjuna was found to be the most potent hypolipidemic agent and induced partial inhibition of rabbit atheroma. The results indicate that T. arjuna may play an anti-atherogenic role. |
| Databáze: | OpenAIRE |
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