Hyper-IgE syndrome: dental implications
| Autor: | Laura Poletti, Alessandro Porro, Giampietro Farronato, Luca Esposito, Paola Pavesi, Rosa Maria Dellepiane, Cinzia Maspero, Maria Cristina Pietrogrande |
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| Rok vydání: | 2011 |
| Předmět: |
Adult
Palate Hard STAT3 Transcription Factor medicine.medical_specialty Adolescent Dental Caries Susceptibility Tooth eruption Dentistry Immunoglobulin E Pathology and Forensic Medicine Young Adult Tongue Eosinophilia medicine Deciduous teeth Humans Radiology Nuclear Medicine and imaging Dentistry (miscellaneous) Young adult Tooth Deciduous Child Tongue Fissured Respiratory Tract Infections Permanent teeth Tooth Eruption Ectopic biology business.industry Tooth Abnormalities Facies medicine.disease Dermatology medicine.anatomical_structure Mutation biology.protein Surgery Oral Surgery Malocclusion business Job Syndrome |
| Zdroj: | Oral surgery, oral medicine, oral pathology and oral radiology. 114(2) |
| ISSN: | 2212-4411 |
| Popis: | Hyper-IgE syndrome (HIES) is a rare multisystem disorder with both immunologic and nonimmunological features. It is characterized by extremely elevated IgE serum levels, eczema, and recurrent skin and pulmonary infections. Dental anomalies are often included, such as retention of deciduous teeth together with ectopic eruption or noneruption of permanent teeth. Severe susceptibility to caries and mycotic infections, insufficient transversal diameter of the palate, mucosal plaques, and fissures typically located on the tongue and on the palate are often present. The aim of this study was to review the literature and to report a 6-year observation of 6 patients with HIES (aged 8-39 years) with focus on their oral problems and the treatment provided. The importance of the role of the dentist both in early diagnosis of this syndrome and in monitoring oral conditions was stressed. The dentist can prevent infective complications and intercept the development of malocclusion with a reduction of the need for complex treatment. |
| Databáze: | OpenAIRE |
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