Effect of the Bruder moist heat eye compress on contact lens discomfort in contact lens wearers: An open-label randomized clinical trial
| Autor: | Kelly K. Nichols, Jason J. Nichols, Paul M. Karpecki, Stephanie Cox, Anna A Tichenor, William Ngo, Jillian F. Ziemanski |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Time Factors Dentistry Meibomian gland law.invention Young Adult 03 medical and health sciences 0302 clinical medicine Randomized controlled trial law Surveys and Questionnaires Humans Medicine Treatment effect business.industry Hyperthermia Induced General Medicine Middle Aged Contact Lenses Hydrophilic Lipid Metabolism Contact lens Ophthalmology medicine.anatomical_structure Tears 030221 ophthalmology & optometry Dry Eye Syndromes Female Open label business 030217 neurology & neurosurgery After treatment Optometry |
| Zdroj: | Contact Lens and Anterior Eye. 42:625-632 |
| ISSN: | 1367-0484 |
| DOI: | 10.1016/j.clae.2019.09.005 |
| Popis: | The purpose of this study was to investigate the effect of the Bruder Moist Heat Compress on contact lens (CL) discomfort in subjects with contact lens-related dry eye (CLDE). This was a 4-week, single-center, three-arm, randomized, open-label clinical trial in subjects diagnosed with CLDE using the Contact Lens Dry Eye Questionnaire. Fifty-one CL wearers were randomized to one of three treatment groups: application of the Bruder Compress twice a day, Bruder Compress once a day, or warm washcloth used for ten minutes twice a day without reheating. Subject diaries were monitored for compliance and collected data on daily CL comfort upon awakening and throughout the afternoon. Clinical assessments included tear film break-up time (TBUT), lipid layer thickness (LLT), and meibomian gland evaluation. Statistical tests included a generalized linear model and one-way analysis of variance (ANOVA) to investigate treatment effect on comfortable wear time. Fifty-one subjects (98% female) completed the study. After treatment, subjects using a washcloth reported more uncomfortable contact lens wear time on average (mean = 5.1 ± 2.8 h) when compared with subjects who had used the Bruder Compress in Group 1 (mean = 2.8 ± 1.6 h) (p = 0.02). In the Bruder Compress groups, there was a significant reduction in the blockage of meibomian glands (p 0.01). No significant difference in uncomfortable wear time was found between subjects using the Bruder Compress twice daily versus once daily (p = 0.48). Subjects using the Bruder Compress once daily had the highest rate of compliance at 90.2% (p 0.01). No significant improvements were observed in TBUT (p = 0.76) or LLT (p = 0.78). The Bruder Moist Heat Compress resulted in a significant improvement in comfortable CL wear time in subjects with CLDE. |
| Databáze: | OpenAIRE |
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