Transepithelial photorefractive keratectomy: a prospective randomized comparative study between the two-step and the single-step techniques

Autor: Mahmoud Abdel-Radi, Mohamed Shehata, Magdi Mohammad Mostafa, Mohamed Omar M. Aly
Rok vydání: 2022
Předmět:
Zdroj: Eye. 37:1545-1552
ISSN: 1476-5454
0950-222X
DOI: 10.1038/s41433-022-02174-4
Popis: Objectives To assess and compare the six-month outcome of the two-step transepithelial phototherapeutic keratectomy- photorefractive keratectomy (PTK-PRK) and the single-step transepithelial PRK for myopia and myopic astigmatism. Methods A prospective randomized study. The study enrolled 100 eyes of 50 patients with mild to moderate myopia or myopic astigmatism stratified into two groups, PTK-PRK (n = 50 eyes) and single step PRK (n = 50 eyes). Primary outcome measures were visual acuity and manifest refraction. Secondary outcome measures were epithelial healing duration, post-PRK pain scores and 3-month postoperative haze grading. Results Preoperative characteristics were similar in both groups (p value > 0.05). The mean uncorrected distance visual acuity (UDVA) at 1 week, 1 month, 3 and 6 months was significantly better in the single-step PRK group than in the two-step PTK-PRK group (p p value p value p value Conclusion The two transepithelial PRK techniques were effective in correcting mild to moderate myopia and myopic astigmatism. However, Single-step transepithelial PRK achieved faster visual recovery, better refractive outcome and shorter epithelial healing time with less post-PRK pain. Clinical trials registry (Clinical Trials.gov Identifier): NCT04710082.
Databáze: OpenAIRE
Externí odkaz: