Hemodialysis in an infant with propoxyphene intoxication
| Autor: | Charles L. Paxson, Theodore J. Buselmeier, Carl M. Kjellstrand, S. Michael Mauer, Barry von Hartizsch |
|---|---|
| Rok vydání: | 1975 |
| Předmět: |
Pharmacology
Drug Dextropropoxyphene Time Factors business.industry media_common.quotation_subject medicine.medical_treatment Propoxyphene Infant Blood Urea Nitrogen Renal Dialysis Anesthesia Tissue binding medicine Intubation Intratracheal Humans Pharmacology (medical) Female Hemodialysis Dialysis clearance business Blood urea nitrogen Dialysis media_common medicine.drug |
| Zdroj: | Clinical pharmacology and therapeutics. 17(1) |
| ISSN: | 0009-9236 |
| Popis: | A 10-month-old infant was treated with intensive supportive care and hemodialysis for severe propoxyphene intoxication. Dialysis clearance studies demonstrated that propoxyphene was removed from the serum at approximately 50% of the rate of blood urea nitrogen removal. Possibly because of tissue binding of the drug, the absolute quantity of propoxyphene removed by dialysis was small. The child survived the acute episode of intoxication but died of pulmonary complications several days later. The role of dialysis in propoxyphene intoxication remains to be established. |
| Databáze: | OpenAIRE |
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