Association of serum FGF-23, klotho, fetuin-A, osteopontin, osteoprotegerin and hs-CRP levels with coronary artery disease

Autor: Naime Sıla Göçer, Ahmet Çağrı Aykan, Kemal Göçer, Metin Kilinc
Rok vydání: 2020
Předmět:
Fibroblast growth factor 23
Male
medicine.medical_specialty
alpha-2-HS-Glycoprotein
Clinical Biochemistry
030232 urology & nephrology
Gene Expression
Coronary Artery Disease
030204 cardiovascular system & hematology
urologic and male genital diseases
Fibroblast growth factor
Coronary Angiography
Severity of Illness Index
Coronary artery disease
03 medical and health sciences
0302 clinical medicine
Osteoprotegerin
Internal medicine
medicine
Humans
Osteopontin
Prospective Studies
Klotho
Klotho Proteins
Aged
Glucuronidase
biology
business.industry
C-reactive protein
General Medicine
Middle Aged
medicine.disease
Fetuin
female genital diseases and pregnancy complications
Fibroblast Growth Factors
Fibroblast Growth Factor-23
Endocrinology
C-Reactive Protein
Case-Control Studies
biology.protein
Female
business
Biomarkers
Zdroj: Scandinavian journal of clinical and laboratory investigation. 80(4)
ISSN: 1502-7686
Popis: Environmental, genetic, oxidative and biochemical factors play an important role in the atherosclerotic process. We investigated the association of serum fibroblast growth factor (FGF-23), klotho, fetuin-A, osteoprotegerin (OPG), osteopontin (OPN) and high-sensitive-CRP (Hs-CRP) markers with coronary artery disease and whether one was superior to others or not. A study group of 52 patients with coronary artery disease (CAD) and a control group of 30 patients with angiographically normal epicardial coronary arteries were included in the study. Serum FGF-23, klotho, fetuin-A, OPN, OPG and Hs-CRP marker levels were studied. Patients with CAD were classified in two groups as low (SYNTAX ≤22
Databáze: OpenAIRE
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