Effect of Probiotics on Constipation, Fecal Azoreductase Activity and Fecal Mucin Content in the Elderly
Autor: | Tarja Suomalainen, Hanna Lagström, Arthur C. Ouwehand, Seppo Salminen |
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Rok vydání: | 2002 |
Předmět: |
Male
medicine.medical_specialty Time Factors Constipation medicine.medical_treatment Laxative Medicine (miscellaneous) Biology Gastroenterology Microbiology law.invention Feces Probiotic fluids and secretions Lactobacillus rhamnosus law Internal medicine medicine Humans NADH NADPH Oxidoreductases Aged Aged 80 and over Nutrition and Dietetics Cathartics Propionibacterium freudenreichii Probiotics Propionibacterium Mucins food and beverages Hydrogen-Ion Concentration Nitroreductases biology.organism_classification Lactobacillus reuteri Intestines Lactobacillus Defecation Female medicine.symptom |
Zdroj: | Annals of Nutrition and Metabolism. 46:159-162 |
ISSN: | 1421-9697 0250-6807 |
Popis: | Background: Constipation is a common problem in elderly subjects, probiotics have been suggested to improve intestinal motility and reduce fecal enzyme activity. Methods: Elderly subjects (n = 28) were enrolled in an open parallel study. The subjects were divided into 3 groups: 1 control group receiving juice; 1 group receiving juice supplemented with Lactobacillus reuteri, and 1 group receiving juice supplemented with Lactobacillus rhamnosus and Propionibacterium freudenreichii. During the first 3 weeks all subjects consumed unsupplemented juice. In the subsequent 4 weeks, the subjects received their designated juice. During the last 3 weeks, all subjects again received unsupplemented juice. From the subjects, defecation frequency, laxative use, fecal pH, mucin content and azoreductase activity were assessed during the last week of each period. Results: The subjects receiving the L. rhamnosus/P. freudenreichii-supplemented juice exhibited a 24% increase in defecation frequency. However, no reduction in laxative use was observed. The fecal azoreductase activity was also significantly reduced in this group. No changes in fecal pH or mucin excretion were observed. Conclusion: Some relief from constipation may be observed with the combination of L. rhamnosus/P. freudenreichii. This probiotic combination also reduced fecal enzyme activity. The tested probiotics did not affect the mucosal barrier. |
Databáze: | OpenAIRE |
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