Relaxation times and microstructures
| Autor: | F. R. Fenrich, Christian Beaulieu, Peter S. Allen |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Cell Membrane Permeability
Magnetic Resonance Spectroscopy Chemical Phenomena Sensitivity and Specificity Diffusion Magnetics Nuclear magnetic resonance Signal-to-noise ratio Animals Humans Radiology Nuclear Medicine and imaging Myelin Sheath Spectroscopy Thermal equilibrium Signal processing Chemistry Physical Chemistry Relaxation (NMR) Resolution (electron density) Water Biological tissue Microstructure Anisotropy Molecular Medicine Nervous System Diseases Protons Biological system Focus (optics) Mathematics |
| Zdroj: | ResearcherID |
| ISSN: | 1099-1492 0952-3480 |
| Popis: | A discussion is presented of the evaluation of multiple relaxation components from water protons in biological tissue. The principal focus is to draw attention to the way in which limitations in the raw NMR data, such as signal-to-noise ratio, data sampling density and acquisition window width, affect the precision and resolution in the processed multiple component solution of the return to thermal equilibrium. The second issue discussed is the interpretation of these multiple components in terms of microstructural compartments of the biological sample and, thirdly, we outline some of the successes in determining regional and pathological variations in microstructure in the human body in-vivo, using the technique of multiple relaxation components. |
| Databáze: | OpenAIRE |
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