Prevalence of and risk factors for methicillin-resistant Staphylococcus aureus colonization among human immunodeficient virus–infected outpatients in Taiwan: oral Candida colonization as a comparator

Autor:	I-Wen Huang, Hui-Ying Wang, Wen-Li Chu, Yun-Liang Yang, Jiun-Nong Lin, Chih-Chao Lin, Chi-Jung Wu, Hsi-Hsun Lin, Li-Yun Hsieh, Hui-Ting Chen, Jui-Fen Lai, Yih-Ru Shiau, Hsiu-Jung Lo, Tsai-Ling Lauderdale, Mao-Wang Ho, Wen Chien Ko
Jazyk:	angličtina
Rok vydání:	2017
Předmět:	0301 basic medicine Microbiology (medical) Staphylococcus aureus Tuberculosis HAART 030106 microbiology Prevalence lcsh:QR1-502 MRSA medicine.disease_cause Article lcsh:Microbiology Microbiology lcsh:Infectious and parasitic diseases 03 medical and health sciences Medicine Dentistry (miscellaneous) Colonization lcsh:RC109-216 oral colonization Candida business.industry SCCmec HIV biochemical phenomena metabolism and nutrition medicine.disease bacterial infections and mycoses Methicillin-resistant Staphylococcus aureus Infectious Diseases Carriage Transferred Article business Viral load
Zdroj:	Journal of Oral Microbiology, Vol 9, Iss 1 (2017) Journal of Oral Microbiology
ISSN:	2000-2297
Popis:	Human immuodeficency virus (HIV)-infected patients receiving highly active antiretroviral therapy (HAART) and community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) have increased in recent years in Taiwan. This study was undertaken to determine the prevalence of and risk factors for nasal and oral S. aureus and MRSA colonization among contemporary HIV-infected populations. Clinical variables for S. aureus and MRSA colonization among HIV-infected outpatients from three hospitals were analyzed and compared with those for oral Candida colonization. Genetic characteristics of MRSA isolates were analyzed. A total of 714 patients were screened for nasal S. aureus colonization, and a subset of 457 patients were also screened for oral S. aureus colonization. Of all patients, 79.4% were receiving HAART, and their mean CD4 count was 472 cells/mm3. The colonization rates in the oral cavity, nasal cavity, and at either site were 18.8%, 31.7%, and 36.8%, respectively, for S. aureus, and 3.1%, 4.4%, and 5.5%, respectively, for MRSA. These rates were all much lower than the previously reported rate of oral Candida colonization (52.4%). By multivariate analysis, a suppressed viral load (
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ef47548144df9d55b81350e08c8c420 https://doaj.org/article/4821358570344303a77025b5cd7ecc35 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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