MRA of the Supraaortic Vasculature: Comparison of Gadobutrol and Gadoterate Meglumine at 1.5 T

Autor: John W. Cerne, Ashitha Pathrose, Alyssa M. Singer, Jackson E. Moore, Ali Serhal, Pascale Aouad, Muhammad Umair, Ann Ragin, Bradley D. Allen, Ryan Avery, Michael Markl, James C. Carr
Rok vydání: 2021
Předmět:
Zdroj: Journal of magnetic resonance imaging : JMRIReferences. 56(2)
ISSN: 1522-2586
Popis: Gadobutrol (GB) and gadoterate meglumine (GM) are contrast agents used for contrast-enhanced magnetic resonance angiography (CEMRA). Supraaortic vasculature (SAV) CEMRAs are used to evaluate stroke risk and neurologic symptoms. There is a need to compare the SAV CEMRA image quality obtained with GB and GM.To intra-individually compare MRA images obtained with equimolar GB and GM at 1.5 T in the SAV.Prospective, crossover.Twenty-eight subjects (54 ± 13 years; 17 female).1.5 T; three-dimensional (3D) gradient recalled echo.Quantitative image quality was measured by normalized signal intensity (SISINo significant difference in SIAt 1.5 T and equimolar demonstration, GB (0.1 mL/kg, i.e., 0.1 mmol/kg) showed higher CRs in the SAV compared to GM (0.2 mL/kg, i.e., 0.1 mmol/kg) at most vessels. Subjective image quality was not significantly different between the two agents for most vessels.2 TECHNICAL EFFICACY: Stage 2.
Databáze: OpenAIRE