Changes in pain profile of patients with haemophilia during 1‐year follow‐up

Autor:	Marie Herzig, Steffen Krüger, T. Hilberg
Rok vydání:	2021
Předmět:	Adult Pain Threshold medicine.medical_specialty Haemophilic arthropathy business.industry Quantitative sensory testing Pain 1 year follow up Hematology General Medicine Middle Aged Hand Hemophilia A Haemophilia medicine.disease medicine.anatomical_structure Internal medicine medicine Humans Ankle business Genetics (clinical) Follow-Up Studies Prophylactic treatment
Zdroj:	Haemophilia. 27:783-792
ISSN:	1365-2516 1351-8216
DOI:	10.1111/hae.14380
Popis:	INTRODUCTION Patients with haemophilia (PwH) may experience increased sensitivity to pain. Based on the assessment of the somatosensory system, a recent study showed a specific pain profile in PwH when compared to controls by using Quantitative Sensory Testing (QST). AIM This study aimed to evaluate the pain profile of affected joints (knee or ankle joints) and a non-affected site (dominant hand) in adult PwH over a 1-year period. METHODS Twenty-four PwH (severe haemophilia A = 19, B = 3; moderate haemophilia A = 1, B = 1; age: 52±8 years) and 21 healthy controls (age: 52±12 years) were examined by QST. Both knee or ankle joints and the hand as reference were examined twice with an interval of 1 year in order to assess several detection (DT) and pain thresholds (PT). RESULTS Statistically significant altered mechanical (P
Databáze:	OpenAIRE
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