Pulmonary Complications of Immunotherapy
Autor: | Brett C. Bade, Jennifer D. Possick |
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Rok vydání: | 2020 |
Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty Lung Neoplasms Pulmonary toxicity medicine.medical_treatment 03 medical and health sciences 0302 clinical medicine Antineoplastic Agents Immunological PD-L1 Medicine Humans 030212 general & internal medicine Adverse effect Lung cancer Intensive care medicine Lung Toxidrome Pneumonitis Chemotherapy biology business.industry Immunotherapy medicine.disease 030228 respiratory system biology.protein business |
Zdroj: | Clinics in chest medicine. 41(2) |
ISSN: | 1557-8216 |
Popis: | Immune checkpoint inhibitor (ICI) therapy represents a paradigm shift in the treatment of patients with locally advanced and metastatic lung cancer. Although immunotherapy generally has a more favorable safety profile when compared with chemotherapy, immune-related adverse events represent important, but incompletely understood, treatment-limiting complications associated with significant morbidity and mortality risk. Current guidelines for diagnosis and management are derived from consensus experience, highlighting that further prospective investigation in this area is needed. As ICI-related pneumonitis is a clinically and radiographically diverse toxidrome, clinical vigilance is important while treating patients with lung cancer. |
Databáze: | OpenAIRE |
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